Articles Posted in antibiotics resistant infections

drug-resistant-fungus-300x228According to the Centers for Disease Control, a multidrug-resistant fungus, Candida auris, is beginning to spread in numerous countries, including the United States where a total of 617 cases have already been reported. Of these cases, 309 have been reported in New York, while Illinois and New Jersey have also reported high numbers and more cases are currently present in nine other states. However, this is not the first time the C. auris fungus has emerged. Symptoms might not be noticeable because patients infected with C. auris are often already sick in the hospital with another serious illness or condition. The symptoms of C. auris infection depend on the body part that is affected. For bloodstream infections, the most common symptoms are fever and chills.

The very first case of the C. auris fungus was discovered in 2009, upon testing of the ear discharge of a patient in Japan. At the time, there were very few reports of the fungus, however throughout 2018 and 2019 such reports are on the rise. Currently, cases of C. auris have also been reported in South America, South Africa, and Asia. It is likely that the fungus was introduced to the United States when a patient or multiple patients received healthcare from an area where the pathogen has already spread and then returned to the United States.

But, what exactly is the fungus and how dangerous is it? One of the major concerns of the C. auris fungus is that it is difficult to diagnose and seemingly impossible to treat given its resistance to multiple antibiotics. This resilient fungus can be spread through contact with a person exposed with fungus or even through objects where the pathogen has colonized. Patients infected with C. auris have been reported to suffer from severe bloodstream and wound infections, as well as ear infections.

The United States Centers for Disease Control and Prevention (CDC) has issued a report based on data from 4000 hospitalizations, which concludes that one in seven infections in acute care hospitals are caused by antibiotic resistant hospital infections.According to the findings, one in seven infections in acute care hospitals, related to catheters and surgeries, are caused by antibiotic-resistant bacteria. Many of the urgent serious antibiotic-resistant bacteria threaten patients while being treated in hospitals for other conditions. Of the 15 urgent serious antibiotic-resistant infections, seven are predominantly acquired in a healthcare setting.
The report highlights the major medical dilemma that antibiotic-resistant bacteria can make infections impossible treat. Antibiotic resistant infections increase patient deaths. In the United States, approximately 2 million persons become ill each year with antibiotic-resistant infections and approximately 23,000 die. The CDC compiled data in 2014 from the National Healthcare Safety Network; taking data on specific infections from 4,000,  short-term acute care hospitals, 501 long-term acute care hospitals and 1,135 inpatient rehabilitation facilities in all 50 states.Researchers found the likelihood of a patient becoming infected by any of the six most common bacteria was 12% for in-patient rehabilitation facilities, and 29% for long term acute care hospitals.

More than half of hospitalized patients are receiving antibiotic treatment on any given day, and one-quarter of that population has a hospital acquired infection, making them more likely to contract illnesses which are resistant to common antibiotic treatment.

Health experts say there is an urgent need to engage new methods of reducing the spread of these superbugs, including finding new ways of treating infections without the use of antibiotics. The National Institute of Allergy and Infectious Diseases (NIAID) recently awarded $5 million to fund research focused on bacterial infection treatments that do not involve the use of antibiotics..  –